eCM (Eur Cell Mater / e Cells & Materials)
eCM Periodical and Conferences, Science with Open Discussion
 ISSN 2522-235X

2021 eCM XX: Biofabrication for Orthopaedics
3rd– 5th December 2021, Congress Center, Davos, Switzerland

Friday, December 3rd


08:45 – 09:15

Martin Stoddart (CH)

Matteo D'Este, Tiziano Serra (CH)
Conference house keeping
Biofabrication, the issues

Session 1: Opening Session and Berton Rahn Award
Chair: Geoff Richards

09:15 - 09:45

Jos Malda (NL)
Berton Rahn winner 2021
Converged biofabrication technologies for osteochondral implants

09:45 - 10:15

Ling Qin (HK)
Berton Rahn winner 2020


10:15 – 10:45 Coffee Break

Session 2: 3D-Printing in the clinical practice
Chair: Jos Malda, David Eglin

10:45 – 11:15

Florian Thieringer (CH)
Virtual surgical planning and medical 3D printing – a fully digital workflow integrated into a point of care setting

11:15 – 11:45

Dietmar Hutmacher (AU)
Bioprinting - Biofabrication - additive biomanufacturing! where is the knowledge we have lost in information?

11:45 – 12:00

FE Weber
Osteoconduction and bone augmentation: When 3D-printed designs
meet bone biology

12:00 – 12:15

L Johansson, JL Latorre-Valenzuela, M Liversain, E Thorel, Y Raymond, MP Ginebra
Clinical applications of 3D-printed patient-specific CaP bone grafts

12:15 – 12:30

X Barceló, K Eichholz, O Garcia, DJ Kelly
3D bioprinting of structurally organized meniscus tissue


Group Photo, Free afternoon & eCM walk

Session 3: Biofabrication strategies
Chair: Tiziano Serra, Sara Palladino

17:00 – 17:30

Joao Mano (PT)
Bioengineering of human tissues using low quantities of soft biomaterials

17:30 – 17:45

G Poologasundarampillai, A Haweet, S Jayash, G Morgan, J Moore Jr, A Candeo
Extrusion bioprinting: novel insights from real-time imaging of cell-hydrogel

17:45 – 18:00

M Camman, P Joanne, G Mosser, C Hélary, O Agbulut
3D printing to design anisotropic and macroporous dense collagen hydrogels to model skeletal muscle

18:00 – 18:15

LP Hatt, S Wirth, A Ristaniemi, K Thompson, D Eglin, MJ Stoddart, AR Armiento
LEGO®-inspired microporous scaffolds for personalised mandibular
bone repair

18:15 - 18:30

S Huber, M Santschi, N Imhof, M Leunig, SJ Ferguson
Meltelectrowritten wave-patterned polycaprolactone constructs reproduce the non-linear elastic behaviour of native acetabular labrum tissue

18:30 – 20:00 Poster session (Drinks & Snacks)


Saturday, December 4th

Session 4: Cartilage
Chair: Sibylle Grad, Pierre Tournier

09:00 - 09:30

M Zenobi-Wong (CH)
Bioprinting at multiple length scales

09:30 – 10:00

Daniel J Kelly (IE)
Biofabrication strategies for cartilage and osteochondral tissue engineering – lessons from failures and successes

10:00 – 10:15

P Guo, C Mini, G Miklosic, A Vernengo, M D'Este, S Grad, M Alini, Z Li
A hydrogel based on decellularized extracellular matrix particles for cartilage regeneration

10:15 – 10:30

AA Gryadunova, J Kasamkattil, MHP Gay, VA Mironov, S Schären, I Martin, A Barbero, O Krupkova, A Mehrkens
Spheroids derived from nasal chondrocytes for nucleus pulposus regeneration

10:30 – 10:45

А Kovalev, S Rodionov, V Kasyanov, S Karshieva, L Koudan, V Mironov
Biomechanical properties of cartilage tissue spheroids: Is there a correlation between the biomechanics of chondrospheres and their regenerative potential in vitro and in vivo?

10:45 – 11:15 Coffee Break

Session 5: Tissue Models
Chair: Christophe Helary, Nicola Di Marzio

11:15 – 11:45

Lorenzo Moroni (NL)
From additive manufacturing to bioprinting: a versatile biofabrication palette for 3D in vitro models and tissue regeneration

11:45 – 12:00

G Graziani, S Farè, E Boanini, G Borciani, S Avnet, T Fischetti, G Di Pompo, M Boi, N Baldini
Development of biomimetic bone models by merging additive manufacturing and nanoscale materials

12:00 – 12:15

D Petta, D D’Arrigo, C Arrigoni, L di Nardo, L Bonetti, L Deabate, C Candrian, S Lopa, M Moretti
Development of a microfluidic arthritic joint model as a screening platform for mesenchymal stem cell therapy


Lunch (Lunch not provided)

Session 6: Bone
Chair: Olivier Guillaume, Daphne van der Heide, Rotsiniaina Randriantsilefisoa

14:30 – 15:00

Alvaro Mata (UK)
Supramolecular engineering of biomaterials for hard tissue regeneration

15:00 – 15:15

KJ Genoud, M Lemoine, EJ Ryan, DJ Kelly, FJ O’Brien
Development of reinforced collagen-hydroxyapatite scaffolds with antibacterial properties using 3D printing to treat bone infection

15:15 – 15:30

J Gehlen, W Qiu, R Müller, XH Qin
Volumetric tomographic photofabrication of living bone-like constructs

15:30 – 15:45

Y Chandorkar, M Valeske, B Kolrosova, M Rottmar, K Maniura-Weber
Bioactive coatings to enhance implant acceptance

15:45 – 16:00

VL Mainardi, C Sabato, M Rubert, A de Leeuw, C Arrigoni, G Dubini, C Candrian, R Müller, M Moretti
Culture of 3D bioprinted bone constructs requires an increased fluid dynamic stimulation

16:00 – 16:15

MA Wesdorp, A Schwab, D Eglin, R Narcisi, GJVM van Osch, M D’Este
A culture model to analyze the acute biomaterial-dependent reaction of human primary neutrophils

18:00 Conference Dinner at Ischalp

Sunday, December 5th

Session 7: Osteochondral Implants
Chair: Catherine Le Visage, Gregor Miklosic, Ezgi Bektas

09:15 – 09:45

Gerjo Van Osch (NL)
Enhancing endogenous repair of osteochondral defects with biomaterials

09:45 – 10:00

ML Terpstra, J Li, A Mensinga, M de Ruijter, MHP van Rijen, C Androulidakis, C Galiotis, I Papantoniou, M Matsusaki, J Malda, R Levato
Bioink with cartilage extracellular matrix microfibers enables spatial control of capillary formation in 3D bioprinted constructs

10:00 – 10:15

R Burdis, F Chariyev-Prinz, DC Browe, FE Freeman, J Nulty, EE McDonnell, KF Eichholz, B Wang, P Brama, DJ Kelly
Spatial patterning of phenotypically distinct microtissues to engineer osteochondral grafts for biological joint resurfacing

10:15 – 10:30

D Kilian, A Lode, M Gelinsky
Design criteria and hybrid biofabrication strategies for the manufactur-ing of patient-specific osteochondral tissue substitutes


10:30 – 11:00 Coffee Break

Session 8: Bioinks and Biomaterial Inks
Chair: Géraldine Guex, Gerjo Van Osch, Stephanie De Oliveira

11:00 – 11:30


11:30 – 11:45

X Du, D Schümperlin, SJ Ferguson
Biofabrication of sodium alginate-silicon nitride/PVA composite biomaterials as a shock-absorbing scaffold

11:45 – 12:00

P Tournier, N Lagneau, J Guicheux, C Le Visage, V Delplace
Clickable dynamic bioinks

12:00 – 12:15

K Singh, JK Wychowaniec, CJC Edwards-Gayle, BJ Rodriguez, DF Brougham
Modulation of cohesive interactions in composite pluronic-PEG based hydrogels enables high resolution 3D extrusion printing

12:15 – 12:30

G Miklosic, C Hélary, SJ Ferguson, M D'Este
Extracellular matrix-based biomaterial ink for the printing of nucleus pulposus-like structures


12:30-14:00 Short lunch (Lunch not provided)


Session 9: Emerging Technologies
Chair: Jacek Wychowaniec, Vianney Delplace

14:00 – 14:30

Riccardo Levato (NL)
Biofabrication of complex volumetric 3D tissues and organoid

14:30 – 15:00

Tiziano Serra (CH)
Sound waves for the assembly and control of tissues organization

15:00 – 15:15

O Guillaume, G Weisgrab, A Arslan, S Van Vlierberghe,A Ovsianikov
Two-photon polymerization for producing cellularized building blocks: new opportunities for orthopaedic repair

15:15 – 15:45

Awards and conference closing

Conference End

We advise all presenters to look at the TIPS FOR TALKS (548 kB) presentation and read these guidelines (39kB) before starting to prepare their talks. Science is in the detail. It is the lifeblood of science to discuss.

All invited talks are 20 minutes (20-30 slides) to allow 10 minutes discussion per talk.
All submitted talks are 10 minutes (10-15 slides) to allow 5 minutes discussion per talk.

Chairpersons will cut people off who try to use this time for their talks!
Please bring a copy of your talk on CD or USB stick to give to Presentation Support, Sunday morning at Registration.

Paper Submission
We invite all keynote speakers to submit a paper (either original research report, original review*or original tutorial*) to the European Cells & Materials (eCM) online 'Open & Free Access' journal.*NOTE: We define a REVIEW PAPER as a paper which includes an extended literature review and complete bibliography (including authors' own work), and can also emphasise authors' new unpublished findings and in an extended discussion puts the topic in proper perspective. A review can also be based on a complete bibliography of an author's own work over several years in relation to others. A TUTORIAL PAPER contains an organised comprehensive review of all relevant published material as for a teaching lecture.


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