eCM (Eur Cell Mater / e Cells & Materials)
eCM Periodical and Conferences, Science with Open Discussion
 ISSN 2522-235X

2018 eCM XVIII: Cartilage & Disc: Repair and Regeneration 25th – 28th June 2018, Congress Center, Davos, Switzerland

Keynote Speakers Include
This is subject to change.

Monday, June 25th
09:00 – 09:15 Welcome
09:15 – 10:45 Session 1 New clinical developments

Keynote 1: Bumsup Lee (Kolon Life Science, Inc, South Korea)
Topic: INVOSSA TM – a cell and gene therapy for osteoarthritis

Keynote 2: Lucienne Vonk (UMC Utrecht, the Netherlands)
Topic: Allogeneic MSCs and autologous chondrons: Clinical applications

Berton Rahn Award Lecture: Daisuke Sakai (Tokai University, Japan)

10:45 – 11:15 Coffee Break

11:15 – 13:00 Session 2 Molecular Profiling

Keynote 1: Stephen M Richardson (The University of Manchester, United Kingdom)
Topic: Nucleus pulposus profiling in development, ageing and degeneration

Keynote 2: Danny Chan (The University of Hong Kong, Hong Kong)
Topic: Lgr5 and Col22a1 mark a committed progenitor lineage to juvenile articular chondrocytes

Free afternoon
17:00 – 18:30 Session 3 Tissue function and dysfunction

Keynote 1: Peter van Der Kraan (Radboud University Medical Center, the Netherlands)
Topic: The role of TGF on cartilage homeostasis

Keynote 2: Richard M Aspden (University of Aberdeen, UK)
Topic: Osteoarthritis as an organ disease

18:30– 20:00 Poster session (Drinks & Snacks)


Tuesday, June 26th

09:00 – 10:45 Session 4 Cells in orthopaedics

Keynote 1: Wiltrud Richter (Heidelberg University Hospital, Germany)
Topic: How articular chondrocytes versus MSC-derived chondrocytes  to respond mechanostimulation?

Keynote 2: Jerome Guicheux (Nantes University Hospital, France)
Topic: Stem cells and biomaterials for the regenerative medicine of intervertebral disc: when tissue engineers meet developmental biologists

10:45 – 11:15 Coffee Break

11:15 – 13:20 Session 5  Immunoregulation

Keynote 1: Yvonne Bastiaansen-Jenniskens (University Medical Center Rotterdam, the Netherlands)
Topic: Immunomodulation in osteoarthritis and cartilage repair

Keynote 3: Raquel M Gonçalves (Universidade do Porto, Portugal)
Topic: Immunomodulatory therapy for the intervertebral disc

Free afternoon

18:00 Conference Dinner


Wednesday, June 27th

09:00 – 10:30 Session 6 Tissue engineering and Regenerative medicine

Keynote 1: Marcy Zenobi-Wong (ETH Zürich, Switzerland)
Topic: Additive Manufacturing of Cartilage Tissues: Promises and Challenges

Keynote 2: Conor T Buckley (Trinity College, Ireland)
Topic: Regeneration of the IVD- Priming and conditioning of cells to function in the disc microenvironment

10:30 – 11:00 Coffee Break

11:00 – 12:30 Session 7 Physical stimulation: Beneficial & Detrimental

Keynote 1: Hans-Joachim Wilke (Ulm University Medical Centre, Germany)
Topic: Effects of multi-axial loading on the intervertebral disc

Keynote 2: Martin Stoddart (AO Research Institute Davos)
Topic: Inducing chondrogenesis by multiaxial load: Cell differentiation and biomarker discovery

Free afternoon


17:00 – 18:30 Session 8 Epigenetic regulation

Keynote 1: H Scott Stadler (Shriners Hospital for Children, USA)
Topic: Regulation of chondrogenesis by the long non coding RNA, lncRNA-HIT

Keynote 2: David Young (Newcastle University, UK)
Topic: miRNA and its role in the articulating joint

18:30 – 20:00 Poster session and Networking (Drinks & Snacks)


Thursday, June 28th

08:30 – 10:30 Session 9
ORS Spine Session
Novel Spine/Intervertebral Disc Diagnostics and Therapeutics

Keynote 1: Nadeen O Chahine (Columbia University, USA)
Topic: Biomarkers for degeneration and back pain

Keynote 2: Benjamin Walter (The Ohio State University, USA)
Topic: Magnetic Resonance Elastography - A clinical tool for in-vivo characterization of the intervertebral disc’s mechanical function

10:30 – 11:00 Coffee Break

11:00 – 12:30 Session 10 Drug and Gene delivery

Keynote 1: Alan Grodzinsky (Massachusetts Institute of Technology, USA)
Topic: Enhancing cartilage drug delivery using electrostatic interactions

Conference summary

Conference End

We advise all presenters to look at the TIPS FOR TALKS (290kB) presentation and read these guidelines (34kB) before starting to prepare their talks. Science is in the detail. It is the lifeblood of science to discuss.
All invited talks are 20 minutes (20-30 slides) to allow 10 minutes discussion per talk.
All submitted talks are 10 minutes (10-15 slides) to allow 5 minutes discussion per talk.
Chairpersons will cut people off who try to use this time for their talks!
Please bring a copy of your talk on CD or USB stick to give to Presentation Support, Sunday morning at Registration.

Paper Submission
We invite all keynote speakers to submit a paper (either original research report, original review*or original tutorial*) to the European Cells & Materials (eCM) online 'Open & Free Access' journal.*NOTE: We define a REVIEW PAPER as a paper which includes an extended literature review and complete bibliography (including authors' own work), and can also emphasise authors' new unpublished findings and in an extended discussion puts the topic in proper perspective. A review can also be based on a complete bibliography of an author's own work over several years in relation to others. A TUTORIAL PAPER contains an organised comprehensive review of all relevant published material as for a teaching lecture.